Race results: Americas MotoGP
| Pos | Num | Rider | Nat | Team | Bike | Time/Gap |
| 1 | 93 | Marc MARQUEZ | ESP | Repsol Honda Team | Honda | 41:41.435 |
| 2 | 20 | Fabio QUARTARARO | FRA | Monster Energy Yamaha MotoGP | Yamaha | +4.679 |
| 3 | 63 | Francesco BAGNAIA | ITA | Ducati Lenovo Team | Ducati | +8.547 |
| 4 | 42 | Alex RINS | ESP | Team SUZUKI ECSTAR | Suzuki | +11.098 |
| 5 | 89 | Jorge MARTIN | ESP | Pramac Racing | Ducati | +11.752 |
| 6 | 23 | Enea BASTIANINI | ITA | Avintia Esponsorama | Ducati | +13.269 |
| 7 | 43 | Jack MILLER | AUS | Ducati Lenovo Team | Ducati | +14.722 |
| 8 | 36 | Joan MIR | ESP | Team SUZUKI ECSTAR | Suzuki | +13.406 |
| 9 | 33 | Brad BINDER | RSA | Red Bull KTM Factory Racing | KTM | +15.832 |
| 10 | 44 | Pol ESPARGARO | ESP | Repsol Honda Team | Honda | +20.265 |
| 11 | 88 | Miguel OLIVEIRA | POR | Red Bull KTM Factory Racing | KTM | +23.055 |
| 12 | 73 | Alex MARQUEZ | ESP | LCR Honda CASTROL | Honda | +24.743 |
| 13 | 4 | Andrea DOVIZIOSO | ITA | Petronas Yamaha SRT | Yamaha | +25.307 |
| 14 | 10 | Luca MARINI | ITA | SKY VR46 Avintia | Ducati | +26.853 |
| 15 | 46 | Valentino ROSSI | ITA | Petronas Yamaha SRT | Yamaha | +28.055 |
| 16 | 27 | Iker LECUONA | ESP | Tech 3 KTM Factory Racing | KTM | +30.989 |
| 17 | 30 | Takaaki NAKAGAMI | JPN | LCR Honda IDEMITSU | Honda | +35.251 |
| 18 | 9 | Danilo PETRUCCI | ITA | Tech 3 KTM Factory Racing | KTM | +42.239 |
| 19 | 21 | Franco MORBIDELLI | ITA | Monster Energy Yamaha MotoGP | Yamaha | +49.854 |
| DNF | 41 | Aleix ESPARGARO | ESP | Aprilia Racing Team Gresini | Aprilia | 12 Laps |
| DNF | 5 | Johann ZARCO | FRA | Pramac Racing | Ducati | 15 Laps |
Race winner: 20 laps
