McLaren could offer Sergio Perez a lifeline should the Mexican be interested in racing in IndyCar next season.
Four-time world champion Vettel will join Lance Stroll at the squad which will be rebranded Aston Martin from next year.
Perez claims he was told nothing about the appointment of Vettel, a point refuted by the team, and has been left with an uncertain future as a result.
In 2019 he signed a new three-year deal with the squad, a contract which has since been torn up to make way for the current Ferrari pilot.
With precious few competitive drives available in Formula 1, McLaren boss Zak Brown has suggested his team could offer Perez a lifeline.
“He'll probably end up in Formula 1, (that) is my guess, at either Haas or Alfa Romeo,” said Brown.
“But if he had an interest in IndyCar, I think he's a great racecar driver, and we'd definitely be interested in talking to him.”
McLaren is involved with IndyCar trough a tie up with Arrow Schmidt Peterson Motorsport.
The Arrow McLaren Racing SP operation fields two Chevrolet powered cars, and also supported Fernando Alonso's entry in the Indianapolis 500.
According to Brown, the addition of Perez would necessitate an expansion of that project to three full-time entries.
“We would need the funding for three cars, and at this point we only have the funding for two cars,” explained Brown.
“So we wouldn't be in a position to sign him today but it would be something that, in-between the backing that he's historically had, and the commercial activity that we've got going on, and the excitement someone like Sergio would create, we would certainly look to see if we could put it together.”
Perez made his Formula 1 debut in 2011 with Sauber, driving for the Swiss-based outfit for two seasons before joining McLaren.
In 2012 he recorded second place finishes at the Malaysian and Italian Grands Prix, which remain career best results.
Since 2014 he's raced with the operation that is today known as Racing Point, establishing himself a solid reputation courtesy of consistent points finishes and occasional podium appearances.