Full results from Free Practice 1 at the Formula 1 Sao Paulo Grand Prix from Interlagos.
| Pos | Num | Driver | Team | Laps | Time | Diff |
| 1 | 11 | Sergio Perez | Red Bull Racing | 28 | 1:11.853 | |
| 2 | 16 | Charles Leclerc | Scuderia Ferrari | 30 | 1:11.857 | +0.004s |
| 3 | 1 | Max Verstappen | Red Bull Racing | 27 | 1:11.861 | +0.008s |
| 4 | 55 | Carlos Sainz | Scuderia Ferrari | 29 | 1:12.039 | +0.186s |
| 5 | 44 | Lewis Hamilton | Mercedes-AMG F1 Team | 24 | 1:12.040 | +0.187s |
| 6 | 63 | George Russell | Mercedes-AMG F1 Team | 23 | 1:12.055 | +0.202s |
| 7 | 5 | Sebastian Vettel | Aston Martin F1 Team | 29 | 1:12.157 | +0.304s |
| 8 | 47 | Mick Schumacher | Haas F1 Team | 26 | 1:12.314 | +0.461s |
| 9 | 77 | Valtteri Bottas | Alfa Romeo F1 Team | 30 | 1:12.466 | +0.613s |
| 10 | 10 | Pierre Gasly | Scuderia AlphaTauri | 31 | 1:12.467 | +0.614s |
| 11 | 14 | Fernando Alonso | Alpine F1 Team | 24 | 1:12.554 | +0.701s |
| 12 | 23 | Alex Albon | Williams Racing | 28 | 1:12.633 | +0.780s |
| 13 | 31 | Esteban Ocon | Alpine F1 Team | 29 | 1:12.705 | +0.852s |
| 14 | 18 | Lance Stroll | Aston Martin F1 Team | 25 | 1:12.759 | +0.906s |
| 15 | 4 | Lando Norris | McLaren F1 Team | 27 | 1:12.955 | +1.102s |
| 16 | 20 | Kevin Magnussen | Haas F1 Team | 24 | 1:12.997 | +1.144s |
| 17 | 6 | Nicholas Latifi | Williams Racing | 31 | 1:13.019 | +1.166s |
| 18 | 24 | Zhou Guanyu | Alfa Romeo F1 Team | 29 | 1:13.115 | +1.262s |
| 19 | 22 | Yuki Tsunoda | Scuderia AlphaTauri | 31 | 1:13.347 | +1.494s |
| 20 | 3 | Daniel Ricciardo | McLaren F1 Team | 27 | 1:13.359 | +1.506s |
